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As you age, protecting your brain probably feels more urgent than ever.

After all, concerns like memory loss and mild cognitive decline become a bigger priority with each passing year.

But when stress, anxiety, or sleep deprivation strike, you might find yourself needing a fast mental reboot.

That’s where one proven herb comes in—clinically shown to boost brainpower in as little as one hour.

In a double-blind, placebo-controlled study, published in the journal Nutrients, researchers from Texas A&M University led by Megan Leonard examined the effects of ashwagandha on brain function.

The study included 59 healthy volunteers with an average age of 23. Participants were randomly assigned to receive either 225 mg of liposomal ashwagandha root and leaf extract (with enhanced absorption) or a placebo daily for 30 days.

Participants took the Computerized Mental Performance Assessment System (COMPASS) cognitive function test at the beginning of the study, one hour after the first dose, and at the end of the month.

The test measured:

  • Word Recall (correct and recalled attempts)
  • Choice Reaction Time (targets identified)
  • Picture Recognition (“yes” correct responses, correct and overall reaction time)
  • Digit Vigilance (correct reaction time)
  • Stroop Color-Word (matching words to colors, reaction time)
  • POMS (tension and fatigue)

After just one hour, the ashwagandha group performed significantly better on cognitive tasks related to memory, attention, vigilance, and executive function.

They also saw improvements in tension and fatigue compared to the placebo group.

What’s more impressive is that the ashwagandha group didn’t just experience short-term benefits. Those gains remained and even improved after 30 days of consistent supplementation.

How does it work?

Researchers suggest ashwagandha influences brain function through several mechanisms: its adaptogenic properties help the body manage stress, it affects GABA activity (an inhibitory neurotransmitter involved in anxiety), it improves sleep quality, and reduces oxidative stress and inflammation.

Ashwagandha is one of the best-known Ayurvedic medicine herbs for good reason. As an adaptogen, it helps your body adapt to stress while providing multiple benefits beyond cognitive enhancement. It’s been well-studied for its ability to reduce anxiety, improve sleep, and boost the immune system.

The study also found that ashwagandha was well-tolerated—either having no impact or even improving clinical blood markers, with no more side effects than a placebo.

If you feel like you could use a little extra brain boost to keep up with life’s demands, consider adding ashwagandha to your routine. Look for a liposomal formulation like the one used in the study, which may offer enhanced absorption at lower doses.

P.S. Is your diet destroying your brain?!

View Sources

Leonard M, Dickerson B, Estes L, Gonzalez DE, Jenkins V, Johnson S, Xing D, Yoo C, Ko J, Purpura M, et al. Acute and Repeated Ashwagandha Supplementation Improves Markers of Cognitive Function and Mood. Nutrients. 2024; 16(12):1813.


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