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Treating depression can be challenging.

Fortunately, there are a handful of lifestyle changes and targeted nutrients that can help—even when medications fall short.

Just recently, I shared how saffron—a gourmet spice—can help ease mood, stress, and sleep troubles in people with depression.

Today, I’ll share the details of another nutrient with significant evidence showing it can improve depression symptoms.

Researchers reviewed the data from 67 clinical trials to find out if omega-3 fatty acids could help treat or prevent depression.

The verdict?

According to the review published in the British Journal of Nutrition, omega-3 fatty acids consistently reduced the severity of depression symptoms. Researchers pinpointed the most effective dose at 1 to 1.5 grams of EPA and DHA omega-3s per day.

One study even showed that taking omega-3s with antidepressants led to greater improvements in depression symptoms than either treatment alone.

Depression is a complicated condition that requires equally complex solutions. Unfortunately, it’s unlikely that any single treatment will fix it.

But when you tackle depression from multiple angles—whether that’s meds, lifestyle changes, or nutrition—you boost your chances of feeling better.

As this review revealed, omega-3s deserve a spot in your depression-fighting arsenal.

Regardless of whether your currently struggling with depression including more omega-3s in your diet is good idea. These powerful anti-inflammatories are vital for your heart, brain, and eye health.

The best food sources of omega-3s include salmon, tuna, sardines, chia seeds, and walnuts. If you eat these foods regularly, you should be able to get all the omega-3s you need for a better mood and better health.

P.S. You’re just two weeks away from a better mood without drugs—here’s how

View Sources

Norouziasl R, Zeraattalab-Motlagh S, Jayedi A, Shab-Bidar S. Efficacy and safety of n-3 fatty acids supplementation on depression: a systematic review and dose–response meta-analysis of randomised controlled trials. British Journal of Nutrition. 2024;131(4):658-671. doi:10.1017/S0007114523002052


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