WWII Era Drug DESTROYS Deadly Superbugs
Antibiotic resistance has us locked in a battle with rapidly morphing superbugs that are learning to evade our best antibiotics.
It’s a race against time. And the superbugs are winning. New drug development takes time that we simply don’t have.
That’s why, instead of creating new antibiotics, a better solution is to take another look at what we ALREADY have.
A few weeks ago, I told you about an incredible new technology that changes a common antibiotic into a shape-shifting Rubik’s cube that prevents resistance. (Read about that remarkable technology here.)
Today, I will share the details of a forgotten World War II era reject that could be the key to beating antibiotic resistance.
Scientific advancements that were once discarded as useless, could actually transform this old-school antibiotic into our saving grace against NEW deadly superbugs.
The antibiotic nourseothricin was discovered in the 1940s. Scientists had high hopes for the drug because it was effective against gram-negative bacteria. These bugs are notoriously difficult to kill with other medications.
The only problem was that it was just as toxic to your kidneys as to these bacteria.
Fortunately, over the past 80-plus years, science has advanced at lightning speed. Scientists are now able to reduce the toxicity of this drug by better purifying the SOURCE of it, streptothricins (a complex molecule with antibiotic properties found in a soil fungus).
In a recent study, scientists tested two forms of highly purified streptothricins: D and F.
While both antibiotics were highly selective for gram-negative bacteria, D was more powerful than F but caused renal toxicity at a lower dose.
They also discovered that nourseothricin kills the bacteria in a way that’s different from other drugs. This suggests the antibiotic could work even when others don’t.
As with most findings at this stage of the game, more research is needed. But it’s a promising start to beating back a deadly health threat.
I’ll keep my eye out for future developments.
In the meantime, you can help make sure the bacteria never take hold, to begin with. It starts with the produce aisle.
If you don’t already get plenty of cruciferous vegetables in your diet, it’s time to start.
When your body digests vegetables like broccoli, Brussels sprouts, cabbage, and kale, a compound called DIM (diindolylmethane) is created.
Research shows this powerful compound could help with antibiotic resistance by reducing biofilm formation in four gram-negative pathogenic bacteria by 80 percent.
P.S. Research reveals that having a healthy microbiome is like an insurance policy against a deadly antibiotic-resistant infection. CLICK HERE for the wholel story.
SOURCE:
“Streptothricin F is a bactericidal antibiotic effective against highly drug-resistant gram-negative bacteria that interacts with the 30S subunit of the 70S ribosome,” PLOS Biology, Published: May 16, 2023, doi.org/10.1371/journal.pbio.3002091