DEADLIEST Cancer Linked to the Sun? (Strange!)
If I were to ask you to name the three things you need to focus on to stay healthy, you’d probably guess diet and exercise immediately.
But I bet you’ll be surprised by the third item on the list.
It’s your circadian rhythm. And although we don’t talk about our internal master clock much, we should.
After all, a disrupted circadian rhythm has been linked to virtually every major disease we battle as we age, including heart disease, type 2 diabetes, hypertension, and obesity.
And now new research has found this same disruption could play a role in what is by far the LEADING cause of cancer death.
You have biological clocks in nearly every single cell in your body. They regulate your sleep-wake cycle over a 24-hour period.
Together they’re called your circadian rhythm. And their importance shouldn’t be underestimated.
If you name a process in your body, chances are these cellular clocks play a part in it. They sync up with the sun’s cycle to regulate your metabolism, immune system, hormones, and more.
This is why people who work the night shift and are out of sync with the sun have a higher risk of many types of cancer. In fact, “the graveyard shift” has even been classified as a possible human carcinogen.
Now, a recent mouse study has given us a better understanding of how circadian disruption can impact your risk of lung cancer.
Mice that were genetically engineered to develop non-small cell lung cancer were housed either:
- under altered light conditions (to simulate the effects of the night shift or jet lag),
- or typical light conditions.
The mice with the disrupted circadian rhythm developed a 68 percent increase in tumor burden during the study’s follow-up period.
But the damage didn’t end there. The researchers also found that the “night shift” mice had disruptions in their genes that regulate the circadian rhythm in their lungs, liver, and spleen.
Specifically, there was an increase in heat shock factor 1 (HSF1) target genes. These genes are associated with increased tumor formation in numerous types of cancer.
When the researchers administered drugs that inhibited the HSF1 genes, it reduced the growth of the lung cancer cells.
As you probably guessed, scientists are already talking about using this type of pharmaceutical approach in people who work the night shift or regularly experience jet lag.
I have a better idea: Fix your circadian rhythm disruption the RIGHT way. And you do that by exposing yourself to MORE sunlight… especially the early morning light.
Then you won’t need drugs. Plus, you’ll get the GOOD side effects of it, reducing the risk for every other major disease in the process.
P.S. Lung cancer kills more men and women than any other type of cancer. But there’s good news. Researchers have identified a way to help STOP lung cancer from spreading to other parts of your body. And it has NOTHING to do with drugs. Click here for the details.
SOURCE:
“Circadian disruption enhances HSF1 signaling and tumorigenesis in Kras-driven lung cancer,” SCIENCE ADVANCES, 28 Sep 2022, Vol 8, Issue 39, DOI: 10.1126/sciadv.abo1123